Poor response to platinum-based chemotherapy is associated with KRAS mutation and concomitant low expression of BRAC1 and TYMS in NSCLC
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چکیده
منابع مشابه
Poor response to platinum-based chemotherapy is associated with KRAS mutation and concomitant low expression of BRAC1 and TYMS in NSCLC
OBJECTIVE To evaluate treatment response, survival, and the associations between KRAS mutation status and tumour expression levels of BRCA1, TYMS and SRC retrospectively in a cohort of patients with non-small cell lung cancer (NSCLC), treated exclusively with conjunctive platinum-based doublet chemotherapy. METHODS KRAS mutation status was determined via amplification refractory mutation and ...
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ژورنال
عنوان ژورنال: Journal of International Medical Research
سال: 2016
ISSN: 0300-0605,1473-2300
DOI: 10.1177/0300060515607383